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Topologically Heterogeneous Beta Cell Adaptation in Response to High-Fat Diet in Mice
AIMS: Beta cells adapt to an increased insulin demand by enhancing insulin secretion via increased beta cell function and/or increased beta cell number. While morphological and functional heterogeneity between individual islets exists, it is unknown whether regional differences in beta cell adaptati...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575501/ https://www.ncbi.nlm.nih.gov/pubmed/23441226 http://dx.doi.org/10.1371/journal.pone.0056922 |