Topologically Heterogeneous Beta Cell Adaptation in Response to High-Fat Diet in Mice

AIMS: Beta cells adapt to an increased insulin demand by enhancing insulin secretion via increased beta cell function and/or increased beta cell number. While morphological and functional heterogeneity between individual islets exists, it is unknown whether regional differences in beta cell adaptati...

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Detalles Bibliográficos
Autores principales: Ellenbroek, Johanne H., Töns, Hendrica A., de Graaf, Natascha, Loomans, Cindy J., Engelse, Marten A., Vrolijk, Hans, Voshol, Peter J., Rabelink, Ton J., Carlotti, Françoise, de Koning, Eelco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575501/
https://www.ncbi.nlm.nih.gov/pubmed/23441226
http://dx.doi.org/10.1371/journal.pone.0056922

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