Co-Introduced Functional CCR2 Potentiates In Vivo Anti-Lung Cancer Functionality Mediated by T Cells Double Gene-Modified to Express WT1-Specific T-Cell Receptor

BACKGROUND AND PURPOSE: Although gene-modification of T cells to express tumor-related antigen-specific T-cell receptor (TCR) or chimeric antigen receptor (CAR) has clinically proved promise, there still remains room to improve the clinical efficacy of re-directed T-cell based antitumor adoptive the...

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Detalles Bibliográficos
Autores principales: Asai, Hiroaki, Fujiwara, Hiroshi, An, Jun, Ochi, Toshiki, Miyazaki, Yukihiro, Nagai, Kozo, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Inoue, Hirofumi, Yasukawa, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575507/
https://www.ncbi.nlm.nih.gov/pubmed/23441216
http://dx.doi.org/10.1371/journal.pone.0056820

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