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Antibiotic Inducibility of the mexXY Multidrug Efflux Operon of Pseudomonas aeruginosa: Involvement of the MexZ Anti-Repressor ArmZ
Expression of the mexXY multidrug efflux operon in wild type Pseudomonas aeruginosa is substantially enhanced by the ribosome-targeting antimicrobial spectinomycin (18-fold) and this is wholly dependent upon the product of the PA5471 gene. In a mutant strain lacking the mexZ gene encoding a represso...
Autores principales: | Hay, Thomas, Fraud, Sebastien, Lau, Calvin Ho-Fung, Gilmour, Christie, Poole, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575510/ https://www.ncbi.nlm.nih.gov/pubmed/23441219 http://dx.doi.org/10.1371/journal.pone.0056858 |
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