Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease

We present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders wit...

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Autores principales: Chiang, David, Lee, Michael, Germaine, Pauline, Liao, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575663/
https://www.ncbi.nlm.nih.gov/pubmed/23431491
http://dx.doi.org/10.1155/2013/190856
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author Chiang, David
Lee, Michael
Germaine, Pauline
Liao, Lydia
author_facet Chiang, David
Lee, Michael
Germaine, Pauline
Liao, Lydia
author_sort Chiang, David
collection PubMed
description We present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders within the left breast. This mass was biopsy proven to represent pleomorphic invasive lobular carcinoma. A pulmonary nodule within the lingula was also noted on the staging bilateral breast MRI and was biopsy proven to represent extranodal Castleman's disease. Therefore, it is believed that our patient had secondary amyloidosis due to Castleman's disease.
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spelling pubmed-35756632013-02-21 Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease Chiang, David Lee, Michael Germaine, Pauline Liao, Lydia Case Rep Radiol Case Report We present an interesting case of focal amyloidosis of the left breast which was intermixed with ductal carcinoma in situ (DCIS). On subsequent staging bilateral breast magnetic resonance imaging (MRI), the patient was found to have an additional suspicious enhancing mass with spiculated borders within the left breast. This mass was biopsy proven to represent pleomorphic invasive lobular carcinoma. A pulmonary nodule within the lingula was also noted on the staging bilateral breast MRI and was biopsy proven to represent extranodal Castleman's disease. Therefore, it is believed that our patient had secondary amyloidosis due to Castleman's disease. Hindawi Publishing Corporation 2013 2013-02-04 /pmc/articles/PMC3575663/ /pubmed/23431491 http://dx.doi.org/10.1155/2013/190856 Text en Copyright © 2013 David Chiang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chiang, David
Lee, Michael
Germaine, Pauline
Liao, Lydia
Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease
title Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease
title_full Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease
title_fullStr Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease
title_full_unstemmed Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease
title_short Amyloidosis of the Breast with Multicentric DCIS and Pleomorphic Invasive Lobular Carcinoma in a Patient with Underlying Extranodal Castleman's Disease
title_sort amyloidosis of the breast with multicentric dcis and pleomorphic invasive lobular carcinoma in a patient with underlying extranodal castleman's disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575663/
https://www.ncbi.nlm.nih.gov/pubmed/23431491
http://dx.doi.org/10.1155/2013/190856
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AT germainepauline amyloidosisofthebreastwithmulticentricdcisandpleomorphicinvasivelobularcarcinomainapatientwithunderlyingextranodalcastlemansdisease
AT liaolydia amyloidosisofthebreastwithmulticentricdcisandpleomorphicinvasivelobularcarcinomainapatientwithunderlyingextranodalcastlemansdisease

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