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Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia

Isovaleric acidemia is a rare branched-chain organic acidemia. The authors describe a 3.5-year-old girl with isovaleric acidemia and acute abdominal pain associated with bilious emesis. Elevated serum amylase and abdominal ultrasonography demonstrating an enlarged and edematous pancreas, along with...

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Autores principales: Mantadakis, Elpis, Chrysafis, Ioannis, Tsouvala, Emmanouela, Evangeliou, Athanassios, Chatzimichael, Athanassios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575664/
https://www.ncbi.nlm.nih.gov/pubmed/23431490
http://dx.doi.org/10.1155/2013/721871
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author Mantadakis, Elpis
Chrysafis, Ioannis
Tsouvala, Emmanouela
Evangeliou, Athanassios
Chatzimichael, Athanassios
author_facet Mantadakis, Elpis
Chrysafis, Ioannis
Tsouvala, Emmanouela
Evangeliou, Athanassios
Chatzimichael, Athanassios
author_sort Mantadakis, Elpis
collection PubMed
description Isovaleric acidemia is a rare branched-chain organic acidemia. The authors describe a 3.5-year-old girl with isovaleric acidemia and acute abdominal pain associated with bilious emesis. Elevated serum amylase and abdominal ultrasonography demonstrating an enlarged and edematous pancreas, along with the presence of peripancreatic exudates, confirmed the presence of acute pancreatitis. The patient recovered quickly with intravenous hydration, pancreatic rest, and administration of intravenous L-carnitine. Pancreatitis should be ruled out in the context of vomiting in any patient with isovaleric acidemia. Conversely, branched-chain organic acidemias should be included in the differential diagnosis of any child with pancreatitis of unknown origin.
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spelling pubmed-35756642013-02-21 Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia Mantadakis, Elpis Chrysafis, Ioannis Tsouvala, Emmanouela Evangeliou, Athanassios Chatzimichael, Athanassios Case Rep Pediatr Case Report Isovaleric acidemia is a rare branched-chain organic acidemia. The authors describe a 3.5-year-old girl with isovaleric acidemia and acute abdominal pain associated with bilious emesis. Elevated serum amylase and abdominal ultrasonography demonstrating an enlarged and edematous pancreas, along with the presence of peripancreatic exudates, confirmed the presence of acute pancreatitis. The patient recovered quickly with intravenous hydration, pancreatic rest, and administration of intravenous L-carnitine. Pancreatitis should be ruled out in the context of vomiting in any patient with isovaleric acidemia. Conversely, branched-chain organic acidemias should be included in the differential diagnosis of any child with pancreatitis of unknown origin. Hindawi Publishing Corporation 2013 2013-02-04 /pmc/articles/PMC3575664/ /pubmed/23431490 http://dx.doi.org/10.1155/2013/721871 Text en Copyright © 2013 Elpis Mantadakis et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mantadakis, Elpis
Chrysafis, Ioannis
Tsouvala, Emmanouela
Evangeliou, Athanassios
Chatzimichael, Athanassios
Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia
title Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia
title_full Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia
title_fullStr Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia
title_full_unstemmed Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia
title_short Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia
title_sort acute pancreatitis with rapid clinical improvement in a child with isovaleric acidemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575664/
https://www.ncbi.nlm.nih.gov/pubmed/23431490
http://dx.doi.org/10.1155/2013/721871
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