Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery

Type 2N Von Willebrand's disease (2N VWD) is a rare, recessively inherited bleeding disorder, comprising 1-2% of all VWD patients, usually manifesting as a mild bleeding diathesis. Treatment includes desmopressin (DDAVP) or intermediate purity plasma-derived FVIII concentrates containing residu...

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Autores principales: Dukka, Srivasavi, Allsup, David John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575673/
https://www.ncbi.nlm.nih.gov/pubmed/23431487
http://dx.doi.org/10.1155/2013/837906
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author Dukka, Srivasavi
Allsup, David John
author_facet Dukka, Srivasavi
Allsup, David John
author_sort Dukka, Srivasavi
collection PubMed
description Type 2N Von Willebrand's disease (2N VWD) is a rare, recessively inherited bleeding disorder, comprising 1-2% of all VWD patients, usually manifesting as a mild bleeding diathesis. Treatment includes desmopressin (DDAVP) or intermediate purity plasma-derived FVIII concentrates containing residual VWF. We present a case of a 75-year-old gentleman, incidentally diagnosed with type 2N VWD in 2002 on routine blood testing before surgery with an ISTH bleeding score of 1-2, who was treated with recombinant FVIII preoperatively.
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spelling pubmed-35756732013-02-21 Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery Dukka, Srivasavi Allsup, David John Case Rep Hematol Case Report Type 2N Von Willebrand's disease (2N VWD) is a rare, recessively inherited bleeding disorder, comprising 1-2% of all VWD patients, usually manifesting as a mild bleeding diathesis. Treatment includes desmopressin (DDAVP) or intermediate purity plasma-derived FVIII concentrates containing residual VWF. We present a case of a 75-year-old gentleman, incidentally diagnosed with type 2N VWD in 2002 on routine blood testing before surgery with an ISTH bleeding score of 1-2, who was treated with recombinant FVIII preoperatively. Hindawi Publishing Corporation 2013 2013-02-03 /pmc/articles/PMC3575673/ /pubmed/23431487 http://dx.doi.org/10.1155/2013/837906 Text en Copyright © 2013 S. Dukka and D. J. Allsup. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dukka, Srivasavi
Allsup, David John
Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery
title Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery
title_full Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery
title_fullStr Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery
title_full_unstemmed Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery
title_short Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery
title_sort perioperative management of type 2n von willebrand's disease with recombinant factor viii in a patient undergoing knee-replacement surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575673/
https://www.ncbi.nlm.nih.gov/pubmed/23431487
http://dx.doi.org/10.1155/2013/837906
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