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Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs

The thymine analog 5-chlorouridine, first reported in the 1950s as anti-tumor agent, is known as an effective mutagen, clastogen and toxicant as well as an effective inducer of sister-chromatid exchange. Recently, the first microorganism with a chemically different genome was reported; the selected...

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Detalles Bibliográficos
Autores principales:	Patra, Amritraj, Harp, Joel, Pallan, Pradeep S., Zhao, Linlin, Abramov, Mikhail, Herdewijn, Piet, Egli, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575798/ https://www.ncbi.nlm.nih.gov/pubmed/23275540 http://dx.doi.org/10.1093/nar/gks1316

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