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Two-dimensional intact mitochondrial DNA agarose electrophoresis reveals the structural complexity of the mammalian mitochondrial genome

The mitochondrial genome exists in numerous structural conformations, complicating the study of mitochondrial DNA (mtDNA) metabolism. Here, we describe the development of 2D intact mtDNA agarose gel electrophoresis (2D-IMAGE) for the separation and detection of approximately two-dozen distinct topoi...

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Detalles Bibliográficos
Autores principales:	Kolesar, Jill E., Wang, Catherine Y., Taguchi, Yumiko V., Chou, Shih-Hsuan, Kaufman, Brett A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575812/ https://www.ncbi.nlm.nih.gov/pubmed/23275548 http://dx.doi.org/10.1093/nar/gks1324

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