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Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis
Human mitochondrial RNA polymerase, POLRMT, is required for mitochondrial DNA (mtDNA) transcription and forms initiation complexes with human mitochondrial transcription factor B2 (h-mtTFB2). However, POLRMT also interacts with the paralogue of h-mtTFB2, h-mtTFB1, which is a 12S ribosomal RNA methyl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575816/ https://www.ncbi.nlm.nih.gov/pubmed/23303773 http://dx.doi.org/10.1093/nar/gks1447 |