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Clostridium difficile TcdC protein binds four-stranded G-quadruplex structures

Clostridium difficile infections are increasing worldwide due to emergence of virulent strains. Infections can result in diarrhea and potentially fatal pseudomembranous colitis. The main virulence factors of C. difficile are clostridial toxins TcdA and TcdB. Transcription of the toxins is positively...

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Detalles Bibliográficos
Autores principales:	van Leeuwen, Hans C., Bakker, Dennis, Steindel, Philip, Kuijper, Ed J., Corver, Jeroen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575817/ https://www.ncbi.nlm.nih.gov/pubmed/23303781 http://dx.doi.org/10.1093/nar/gks1448

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