A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing

Mycobacteria have two genetically distinct pathways for the homology-directed repair of DNA double-strand breaks: homologous recombination (HR) and single-strand annealing (SSA). HR is abolished by deletion of RecA and reduced in the absence of the AdnAB helicase/nuclease. By contrast, SSA is RecA-i...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Richa, Ryzhikov, Mikhail, Koroleva, Olga, Unciuleac, Mihaela, Shuman, Stewart, Korolev, Sergey, Glickman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575820/
https://www.ncbi.nlm.nih.gov/pubmed/23295671
http://dx.doi.org/10.1093/nar/gks1298

Ejemplares similares

Ejemplares similares