Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome

Single-stranded DNA (ssDNA) binding proteins are important in basal metabolic pathways for gene transcription, recombination, DNA repair and replication in all domains of life. Their main cellular role is to stabilize melted duplex DNA and protect genomic DNA from degradation. We have uncovered the...

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Detalles Bibliográficos
Autores principales: Rossi, Paolo, Barbieri, Christopher M., Aramini, James M., Bini, Elisabetta, Lee, Hsiau-Wei, Janjua, Haleema, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575825/
https://www.ncbi.nlm.nih.gov/pubmed/23303792
http://dx.doi.org/10.1093/nar/gks1348

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