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Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy

Single-molecule techniques facilitate analysis of mechanical transitions within nucleic acids and proteins. Here, we describe an integrated fluorescence and magnetic tweezers instrument that permits detection of nanometer-scale DNA structural rearrangements together with the application of a wide ra...

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Detalles Bibliográficos
Autores principales:	Long, Xi, Parks, Joseph W., Bagshaw, Clive R., Stone, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575832/ https://www.ncbi.nlm.nih.gov/pubmed/23303789 http://dx.doi.org/10.1093/nar/gks1341

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