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DNA target sequence identification mechanism for dimer-active protein complexes

Sequence-specific DNA-binding proteins must quickly and reliably localize specific target sites on DNA. This search process has been well characterized for monomeric proteins, but it remains poorly understood for systems that require assembly into dimers or oligomers at the target site. We present a...

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Detalles Bibliográficos
Autores principales: Landry, Markita P., Zou, Xueqing, Wang, Lei, Huang, Wai Mun, Schulten, Klaus, Chemla, Yann R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575837/
https://www.ncbi.nlm.nih.gov/pubmed/23275566
http://dx.doi.org/10.1093/nar/gks1345

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