Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop

Paternal duplications of chromosome 6q24, a region that contains the imprinted PLAGL1 and HYMAI transcripts, are associated with transient neonatal diabetes mellitus. A common feature of imprinted genes is that they tend to cluster together, presumably as a result of sharing common cis-acting regula...

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Detalles Bibliográficos
Autores principales: Iglesias-Platas, Isabel, Court, Franck, Camprubi, Cristina, Sparago, Angela, Guillaumet-Adkins, Amy, Martin-Trujillo, Alex, Riccio, Andrea, Moore, Gudrun E., Monk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575839/
https://www.ncbi.nlm.nih.gov/pubmed/23295672
http://dx.doi.org/10.1093/nar/gks1355

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