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TrueSight: a new algorithm for splice junction detection using RNA-seq

RNA-seq has proven to be a powerful technique for transcriptome profiling based on next-generation sequencing (NGS) technologies. However, due to the short length of NGS reads, it is challenging to accurately map RNA-seq reads to splice junctions (SJs), which is a critically important step in the an...

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Detalles Bibliográficos
Autores principales: Li, Yang, Li-Byarlay, Hongmei, Burns, Paul, Borodovsky, Mark, Robinson, Gene E., Ma, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575843/
https://www.ncbi.nlm.nih.gov/pubmed/23254332
http://dx.doi.org/10.1093/nar/gks1311