Regulation of the FOXO3a/Bim signaling pathway by 5,7-dihydroxy-8-nitrochrysin in MDA-MB-453 breast cancer cells

We previously demonstrated that 5,7-dihydroxy-8-nitrochrysin (NOC), a novel synthetic chrysin analog, preferentially inhibits HER-2/neu-overexpressing MDA-MB-453 breast cancer cell growth by inducing apoptosis; however, the precise molecular mechanism was unclear. In this study, we demonstrated that...

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Detalles Bibliográficos
Autores principales: ZHAO, XIAO-CHUN, CAO, XIAO-CHENG, LIU, FEI, QUAN, MEI-FANG, REN, KAI-QUN, CAO, JIAN-GUO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576196/
https://www.ncbi.nlm.nih.gov/pubmed/23425937
http://dx.doi.org/10.3892/ol.2012.1077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576196/
https://www.ncbi.nlm.nih.gov/pubmed/23425937
http://dx.doi.org/10.3892/ol.2012.1077

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