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Prognostication of prostate cancer based on TOP2A protein and gene assessment: TOP2A in prostate cancer

BACKGROUND: TOP2A encodes for topoisomerase IIα, a nuclear enzyme that controls DNA topological structure and cell cycle progression. This enzyme is a marker of cell proliferation in normal and neoplastic tissues; however, little information is available about its expression in prostate cancer (PCa)...

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Detalles Bibliográficos
Autores principales: de Resende, Marina França, Vieira, Samantha, Chinen, Ludmilla Thomé Domingos, Chiappelli, Francesco, da Fonseca, Francisco Paulo, Guimarães, Gustavo Cardoso, Soares, Fernando Augusto, Neves, Ivan, Pagotty, Simone, Pellionisz, Peter A, Barkhordarian, Andre, Brant, Xenia, Rocha, Rafael Malagoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576277/
https://www.ncbi.nlm.nih.gov/pubmed/23398928
http://dx.doi.org/10.1186/1479-5876-11-36