Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

BACKGROUND: Pancreatic cancer is characterized by constitutive activation of mitogen-activated protein kinase (MAPK). Activation of MAPK is associated with the upregulation of genes implicated in the proliferation and survival of pancreatic cancer cells. We hypothesized that knockdown of these MAPK-...

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Detalles Bibliográficos
Autores principales: Furukawa, Toru, Tanji, Etsuko, Kuboki, Yuko, Hatori, Takashi, Yamamoto, Masakazu, Shimizu, Kyoko, Shibata, Noriyuki, Shiratori, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576306/
https://www.ncbi.nlm.nih.gov/pubmed/23227827
http://dx.doi.org/10.1186/1476-4598-11-88

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