Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90

The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. Among attractive drugs, calpain inhibitor that inhibits programmed cell death ‘apoptosis’ is a candidate for curing apoptosis-mediated intractable diseases such as Alzheimer’s disease an...

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Detalles Bibliográficos
Autores principales: Baba, Koichi, Nishida, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576309/
https://www.ncbi.nlm.nih.gov/pubmed/22863139
http://dx.doi.org/10.1186/1556-276X-7-436
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author Baba, Koichi
Nishida, Kohji
author_facet Baba, Koichi
Nishida, Kohji
author_sort Baba, Koichi
collection PubMed
description The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. Among attractive drugs, calpain inhibitor that inhibits programmed cell death ‘apoptosis’ is a candidate for curing apoptosis-mediated intractable diseases such as Alzheimer’s disease and Parkinson’s disease. In this study, the preparation of calpain inhibitor nanocrystals using Nano Spray Dryer B-90 was demonstrated. The particle sizes were controlled by means of selecting mesh aperture sizes. The obtained average particle sizes were in the range of around 300 nm to submicron meter.
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spelling pubmed-35763092013-02-20 Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90 Baba, Koichi Nishida, Kohji Nanoscale Res Lett Nano Express The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. Among attractive drugs, calpain inhibitor that inhibits programmed cell death ‘apoptosis’ is a candidate for curing apoptosis-mediated intractable diseases such as Alzheimer’s disease and Parkinson’s disease. In this study, the preparation of calpain inhibitor nanocrystals using Nano Spray Dryer B-90 was demonstrated. The particle sizes were controlled by means of selecting mesh aperture sizes. The obtained average particle sizes were in the range of around 300 nm to submicron meter. Springer 2012-08-04 /pmc/articles/PMC3576309/ /pubmed/22863139 http://dx.doi.org/10.1186/1556-276X-7-436 Text en Copyright ©2012 Baba and Nishida.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Nano Express
Baba, Koichi
Nishida, Kohji
Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90
title Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90
title_full Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90
title_fullStr Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90
title_full_unstemmed Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90
title_short Calpain inhibitor nanocrystals prepared using Nano Spray Dryer B-90
title_sort calpain inhibitor nanocrystals prepared using nano spray dryer b-90
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576309/
https://www.ncbi.nlm.nih.gov/pubmed/22863139
http://dx.doi.org/10.1186/1556-276X-7-436
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