SKLB023 Blocks Joint Inflammation and Cartilage Destruction in Arthritis Models via Suppression of Nuclear Factor-Kappa B Activation in Macrophage

Rheumatoid arthritis (RA) is the most common arthritis and is mainly characterized by symmetric polyarticular joint disorders. Our previous study demonstrated a novel small molecule compound (Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin-5-ylidene) methyl) phenoxy) acet-amide (SKLB023) showed po...

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Detalles Bibliográficos
Autores principales: Xie, Caifeng, Ma, Liang, Liu, Juan, Li, Xiuxia, Pei, Heying, Xiang, Mingli, Chen, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576337/
https://www.ncbi.nlm.nih.gov/pubmed/23431370
http://dx.doi.org/10.1371/journal.pone.0056349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576337/
https://www.ncbi.nlm.nih.gov/pubmed/23431370
http://dx.doi.org/10.1371/journal.pone.0056349

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