iASeq: integrative analysis of allele-specificity of protein-DNA interactions in multiple ChIP-seq datasets

BACKGROUND: ChIP-seq provides new opportunities to study allele-specific protein-DNA binding (ASB). However, detecting allelic imbalance from a single ChIP-seq dataset often has low statistical power since only sequence reads mapped to heterozygote SNPs are informative for discriminating two alleles...

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Detalles Bibliográficos
Autores principales: Wei, Yingying, Li, Xia, Wang, Qian-fei, Ji, Hongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576346/
https://www.ncbi.nlm.nih.gov/pubmed/23194258
http://dx.doi.org/10.1186/1471-2164-13-681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576346/
https://www.ncbi.nlm.nih.gov/pubmed/23194258
http://dx.doi.org/10.1186/1471-2164-13-681

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