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iASeq: integrative analysis of allele-specificity of protein-DNA interactions in multiple ChIP-seq datasets
BACKGROUND: ChIP-seq provides new opportunities to study allele-specific protein-DNA binding (ASB). However, detecting allelic imbalance from a single ChIP-seq dataset often has low statistical power since only sequence reads mapped to heterozygote SNPs are informative for discriminating two alleles...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576346/ https://www.ncbi.nlm.nih.gov/pubmed/23194258 http://dx.doi.org/10.1186/1471-2164-13-681 |