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Mouse Zygotes Respond to Severe Sperm DNA Damage by Delaying Paternal DNA Replication and Embryonic Development

Mouse zygotes do not activate apoptosis in response to DNA damage. We previously reported a unique form of inducible sperm DNA damage termed sperm chromatin fragmentation (SCF). SCF mirrors some aspects of somatic cell apoptosis in that the DNA degradation is mediated by reversible double strand bre...

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Detalles Bibliográficos
Autores principales:	Gawecka, Joanna E., Marh, Joel, Ortega, Michael, Yamauchi, Yasuhiro, Ward, Monika A., Ward, W. Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576397/ https://www.ncbi.nlm.nih.gov/pubmed/23431372 http://dx.doi.org/10.1371/journal.pone.0056385

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