Direct detection pays off for electron cryo-microscopy

Improved electron detectors and image-processing techniques will allow the structures of macromolecules to be determined from tens of thousands of single-particle cryo-EM images, rather than the hundreds of thousands needed previously.

Detalles Bibliográficos
Autor principal: Grigorieff, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576708/
https://www.ncbi.nlm.nih.gov/pubmed/23426864
http://dx.doi.org/10.7554/eLife.00573
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author Grigorieff, Nikolaus
author_facet Grigorieff, Nikolaus
author_sort Grigorieff, Nikolaus
collection PubMed
description Improved electron detectors and image-processing techniques will allow the structures of macromolecules to be determined from tens of thousands of single-particle cryo-EM images, rather than the hundreds of thousands needed previously.
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spelling pubmed-35767082013-02-20 Direct detection pays off for electron cryo-microscopy Grigorieff, Nikolaus eLife Biophysics and Structural Biology Improved electron detectors and image-processing techniques will allow the structures of macromolecules to be determined from tens of thousands of single-particle cryo-EM images, rather than the hundreds of thousands needed previously. eLife Sciences Publications, Ltd 2013-02-19 /pmc/articles/PMC3576708/ /pubmed/23426864 http://dx.doi.org/10.7554/eLife.00573 Text en Copyright © 2013, Grigorieff http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Biophysics and Structural Biology
Grigorieff, Nikolaus
Direct detection pays off for electron cryo-microscopy
title Direct detection pays off for electron cryo-microscopy
title_full Direct detection pays off for electron cryo-microscopy
title_fullStr Direct detection pays off for electron cryo-microscopy
title_full_unstemmed Direct detection pays off for electron cryo-microscopy
title_short Direct detection pays off for electron cryo-microscopy
title_sort direct detection pays off for electron cryo-microscopy
topic Biophysics and Structural Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576708/
https://www.ncbi.nlm.nih.gov/pubmed/23426864
http://dx.doi.org/10.7554/eLife.00573
work_keys_str_mv AT grigorieffnikolaus directdetectionpaysoffforelectroncryomicroscopy

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