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Mechanism of Tetracycline Resistance by Ribosomal Protection Protein Tet(O)
Tetracycline resistance protein Tet(O), which protects the bacterial ribosome from binding the antibiotic tetracycline, is a translational GTPase with significant similarity in both sequence and structure to the elongation factor EF-G. Here, we present an atomic model of the Tet(O)-bound 70S ribosom...
Autores principales: | Li, Wen, Atkinson, Gemma C., Thakor, Nehal S., Allas, Ülar, Lu, Chuao-chao, Chan, Kwok-Yan, Tenson, Tanel, Schulten, Klaus, Wilson, Kevin S., Hauryliuk, Vasili, Frank, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576927/ https://www.ncbi.nlm.nih.gov/pubmed/23403578 http://dx.doi.org/10.1038/ncomms2470 |
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