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Intracellular calcium release modulates polycystin-2 trafficking

BACKGROUND: Polycystin-2 (PC2), encoded by the gene that is mutated in autosomal dominant polycystic kidney disease (ADPKD), functions as a calcium (Ca(2+)) permeable ion channel. Considerable controversy remains regarding the subcellular localization and signaling function of PC2 in kidney cells. M...

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Detalles Bibliográficos
Autores principales:	Miyakawa, Ayako, Ibarra, Cristián, Malmersjö, Seth, Aperia, Anita, Wiklund, Peter, Uhlén, Per
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577431/ https://www.ncbi.nlm.nih.gov/pubmed/23398808 http://dx.doi.org/10.1186/1471-2369-14-34

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