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Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression
BACKGROUND: Lewy bodies (LB) are a neuropathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. The role their formation plays in disease pathogenesis is not well understood, in part because studies of LB have been limited to examination of post-mortem tissue. LB formation may...
Autores principales: | Cronin-Furman, Emily N, Borland, M Kathleen, Bergquist, Kristen E, Bennett, James P, Trimmer, Patricia A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577453/ https://www.ncbi.nlm.nih.gov/pubmed/23351342 http://dx.doi.org/10.1186/1750-1326-8-6 |
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