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Channel-mediated astrocytic glutamate release via Bestrophin-1 targets synaptic NMDARs
BACKGROUND: Astrocytes regulate neuronal excitability and synaptic activity by releasing gliotransmitters such as glutamate. Our recent study demonstrated that astrocytes release glutamate upon GPCR activation via Ca(2+) activated anion channel, Bestrophin-1 (Best1). The target of Best1-mediated ast...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577500/ https://www.ncbi.nlm.nih.gov/pubmed/23324492 http://dx.doi.org/10.1186/1756-6606-6-4 |