Lapatinib-Binding Protein Kinases in the African Trypanosome: Identification of Cellular Targets for Kinase-Directed Chemical Scaffolds

Human African trypanosomiasis is caused by the eukaryotic microbe Trypanosoma brucei. To discover new drugs against the disease, one may use drugs in the clinic for other indications whose chemical scaffolds can be optimized via a medicinal chemistry campaign to achieve greater potency against the t...

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Detalles Bibliográficos
Autores principales: Katiyar, Samiksha, Kufareva, Irina, Behera, Ranjan, Thomas, Sarah M., Ogata, Yuko, Pollastri, Michael, Abagyan, Ruben, Mensa-Wilmot, Kojo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577790/
https://www.ncbi.nlm.nih.gov/pubmed/23437089
http://dx.doi.org/10.1371/journal.pone.0056150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577790/
https://www.ncbi.nlm.nih.gov/pubmed/23437089
http://dx.doi.org/10.1371/journal.pone.0056150

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