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Lapatinib-Binding Protein Kinases in the African Trypanosome: Identification of Cellular Targets for Kinase-Directed Chemical Scaffolds
Human African trypanosomiasis is caused by the eukaryotic microbe Trypanosoma brucei. To discover new drugs against the disease, one may use drugs in the clinic for other indications whose chemical scaffolds can be optimized via a medicinal chemistry campaign to achieve greater potency against the t...
Autores principales: | Katiyar, Samiksha, Kufareva, Irina, Behera, Ranjan, Thomas, Sarah M., Ogata, Yuko, Pollastri, Michael, Abagyan, Ruben, Mensa-Wilmot, Kojo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577790/ https://www.ncbi.nlm.nih.gov/pubmed/23437089 http://dx.doi.org/10.1371/journal.pone.0056150 |
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