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Human α4β2 Nicotinic Acetylcholine Receptor as a Novel Target of Oligomeric α-Synuclein

Cigarette smoking is associated with a decreased incidence of Parkinson disease (PD) through unknown mechanisms. Interestingly, a decrease in the numbers of α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) in PD patients suggests an α4β2-nAChR-mediated cholinergic deficit in PD. Although oligome...

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Detalles Bibliográficos
Autores principales:	Liu, Qiang, Emadi, Sharareh, Shen, Jian-Xin, Sierks, Michael R., Wu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577813/ https://www.ncbi.nlm.nih.gov/pubmed/23437071 http://dx.doi.org/10.1371/journal.pone.0055886

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