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Elucidating the Landscape of Aberrant DNA Methylation in Hepatocellular Carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers and frequently presents with an advanced disease at diagnosis. There is only limited knowledge of genome-scale methylation changes in HCC. METHODS AND FINDINGS: We performed genome-wide methylation profiling in a total of 4...

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Detalles Bibliográficos
Autores principales: Song, Min-Ae, Tiirikainen, Maarit, Kwee, Sandi, Okimoto, Gordon, Yu, Herbert, Wong, Linda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577824/
https://www.ncbi.nlm.nih.gov/pubmed/23437062
http://dx.doi.org/10.1371/journal.pone.0055761