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Bmi1 Enhances Tumorigenicity and Cancer Stem Cell Function in Pancreatic Adenocarcinoma

BACKGROUND: Bmi1 is an integral component of the Polycomb Repressive Complex 1 (PRC1) and is involved in the pathogenesis of multiple cancers. It also plays a key role in the functioning of endogenous stem cells and cancer stem cells. Previous work implicated a role for cancer stem cells in the path...

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Detalles Bibliográficos
Autores principales:	Proctor, Erica, Waghray, Meghna, Lee, Cheong Jun, Heidt, David G., Yalamanchili, Malica, Li, Chenwei, Bednar, Filip, Simeone, Diane M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577834/ https://www.ncbi.nlm.nih.gov/pubmed/23437065 http://dx.doi.org/10.1371/journal.pone.0055820

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