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The Dynamics of Stress p53-Mdm2 Network Regulated by p300 and HDAC1

We construct a stress p53-Mdm2-p300-HDAC1 regulatory network that is activated and stabilised by two regulatory proteins, p300 and HDAC1. Different activation levels of [Image: see text] observed due to these regulators during stress condition have been investigated using a deterministic as well as...

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Detalles Bibliográficos
Autores principales: Arora, Akshit, Gera, Saurav, Maheshwari, Tanuj, Raghav, Dhwani, Alam, Md. Jahoor, Singh, R. K. Brojen, Agarwal, Subhash M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577848/
https://www.ncbi.nlm.nih.gov/pubmed/23437037
http://dx.doi.org/10.1371/journal.pone.0052736