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Derivation of a Germline Competent Transgenic Fischer 344 Embryonic Stem Cell Line
Embryonic stem (ES) cell-based gene manipulation is an effective method for the generation of mutant animal models in mice and rats. Availability of germline-competent ES cell lines from inbred rat strains would allow for creation of new genetically modified models in the desired genetic background....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577902/ https://www.ncbi.nlm.nih.gov/pubmed/23437152 http://dx.doi.org/10.1371/journal.pone.0056518 |