Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer

Two major populations of myeloid-derived suppressor cells (MDSC), monocytic MDSC (M-MDSC) and polymorphonuclear MDSC (PMN-MDSC) regulate immune responses in cancer and other pathologic conditions. Under physiologic conditions, Ly6C(hi)Ly6G(−) inflammatory monocytes, which are the normal counterpart...

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Detalles Bibliográficos
Autores principales: Youn, Je-In, Kumar, Vinit, Collazo, Michelle, Nefedova, Yulia, Condamine, Thomas, Cheng, Pingyan, Villagra, Alejandro, Antonia, Scott, McCaffrey, Judith C., Fishman, Mayer, Sarnaik, Amod, Horna, Pedro, Sotomayor, Eduardo, Gabrilovich, Dmitry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578019/
https://www.ncbi.nlm.nih.gov/pubmed/23354483
http://dx.doi.org/10.1038/ni.2526

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