Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient

Immune reconstitution inflammatory syndrome (IRIS) refers to the presence of paradoxical clinical deterioration attributable to immune system recovery during highly active antiretroviral therapy (HAART). We present an immunocompetent patient with multifocal leukoencephalopathy on HAART, with central...

Descripción completa

Detalles Bibliográficos
Autores principales: Hornik, Alejandro, Rodriguez-Porcel, Federico, Wallery, Shawn, Flaster, Murray, Lee, John M., Biller, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578199/
https://www.ncbi.nlm.nih.gov/pubmed/23439663
http://dx.doi.org/10.3389/fneur.2013.00012
_version_ 1782260009370910720
author Hornik, Alejandro
Rodriguez-Porcel, Federico
Wallery, Shawn
Flaster, Murray
Lee, John M.
Biller, José
author_facet Hornik, Alejandro
Rodriguez-Porcel, Federico
Wallery, Shawn
Flaster, Murray
Lee, John M.
Biller, José
author_sort Hornik, Alejandro
collection PubMed
description Immune reconstitution inflammatory syndrome (IRIS) refers to the presence of paradoxical clinical deterioration attributable to immune system recovery during highly active antiretroviral therapy (HAART). We present an immunocompetent patient with multifocal leukoencephalopathy on HAART, with central nervous system (CNS) IRIS pathology of unknown infectious etiology. CNS IRIS pathology should be suspected in patients on longstanding HAART without immune reconstitution, presenting with unexplained leukoencephalopathy.
format Online
Article
Text
id pubmed-3578199
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-35781992013-02-22 Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient Hornik, Alejandro Rodriguez-Porcel, Federico Wallery, Shawn Flaster, Murray Lee, John M. Biller, José Front Neurol Neuroscience Immune reconstitution inflammatory syndrome (IRIS) refers to the presence of paradoxical clinical deterioration attributable to immune system recovery during highly active antiretroviral therapy (HAART). We present an immunocompetent patient with multifocal leukoencephalopathy on HAART, with central nervous system (CNS) IRIS pathology of unknown infectious etiology. CNS IRIS pathology should be suspected in patients on longstanding HAART without immune reconstitution, presenting with unexplained leukoencephalopathy. Frontiers Media S.A. 2013-02-21 /pmc/articles/PMC3578199/ /pubmed/23439663 http://dx.doi.org/10.3389/fneur.2013.00012 Text en Copyright © 2013 Hornik, Rodriguez-Porcel, Wallery, Flaster, Lee and Biller. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Neuroscience
Hornik, Alejandro
Rodriguez-Porcel, Federico
Wallery, Shawn
Flaster, Murray
Lee, John M.
Biller, José
Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient
title Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient
title_full Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient
title_fullStr Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient
title_full_unstemmed Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient
title_short Late Onset CNS Immune Reconstitution Inflammatory Syndrome in an Immunocompetent Patient
title_sort late onset cns immune reconstitution inflammatory syndrome in an immunocompetent patient
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578199/
https://www.ncbi.nlm.nih.gov/pubmed/23439663
http://dx.doi.org/10.3389/fneur.2013.00012
work_keys_str_mv AT hornikalejandro lateonsetcnsimmunereconstitutioninflammatorysyndromeinanimmunocompetentpatient
AT rodriguezporcelfederico lateonsetcnsimmunereconstitutioninflammatorysyndromeinanimmunocompetentpatient
AT walleryshawn lateonsetcnsimmunereconstitutioninflammatorysyndromeinanimmunocompetentpatient
AT flastermurray lateonsetcnsimmunereconstitutioninflammatorysyndromeinanimmunocompetentpatient
AT leejohnm lateonsetcnsimmunereconstitutioninflammatorysyndromeinanimmunocompetentpatient
AT billerjose lateonsetcnsimmunereconstitutioninflammatorysyndromeinanimmunocompetentpatient

Ejemplares similares