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The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pathways
Despite recent advances in radiotherapy, chemotherapy, and surgical techniques, glioblastoma multiforme (GBM) prognosis remains dismal. There is an urgent need for new therapeutic strategies. Nanoparticles of biodegradable polymers for anticancer drug delivery have attracted intense interest in rece...
Autores principales: | Bernardi, Andressa, Frozza, Rudimar L, Hoppe, Juliana B, Salbego, Christianne, Pohlmann, Adriana R, Battastini, Ana Maria O, Guterres, Sílvia S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578504/ https://www.ncbi.nlm.nih.gov/pubmed/23440594 http://dx.doi.org/10.2147/IJN.S40284 |
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