The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury

The migration of polymorphonuclear granulocytes (PMN) into the brain parenchyma and release of their abundant proteases are considered the main causes of neuronal cell death and reperfusion injury following ischemia. Yet, therapies targeting PMN egress have been largely ineffective. To address this...

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Detalles Bibliográficos
Autores principales: Enzmann, Gaby, Mysiorek, Caroline, Gorina, Roser, Cheng, Yu-Jung, Ghavampour, Sharang, Hannocks, Melanie-Jane, Prinz, Vincent, Dirnagl, Ulrich, Endres, Matthias, Prinz, Marco, Beschorner, Rudi, Harter, Patrick N., Mittelbronn, Michel, Engelhardt, Britta, Sorokin, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578720/
https://www.ncbi.nlm.nih.gov/pubmed/23269317
http://dx.doi.org/10.1007/s00401-012-1076-3

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