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Role of Epigenetics in Chronic Myeloid Leukemia

The efficacy of therapeutic modalities in chronic myeloid leukemia (CML) depends on both genetic and epigenetic mechanisms. This review focuses on epigenetic mechanisms involved in the pathogenesis of CML and in resistance of tumor cells to tyrosine kinase inhibitors leading to the leukemic clone es...

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Detalles Bibliográficos
Autores principales: Machova Polakova, Katerina, Koblihova, Jitka, Stopka, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Science Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578734/
https://www.ncbi.nlm.nih.gov/pubmed/23296408
http://dx.doi.org/10.1007/s11899-012-0152-z