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Significantly Improved HIV Inhibitor Efficacy Prediction Employing Proteochemometric Models Generated From Antivirogram Data

Infection with HIV cannot currently be cured; however it can be controlled by combination treatment with multiple anti-retroviral drugs. Given different viral genotypes for virtually each individual patient, the question now arises which drug combination to use to achieve effective treatment. With t...

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Detalles Bibliográficos
Autores principales: van Westen, Gerard J. P., Hendriks, Alwin, Wegner, Jörg K., IJzerman, Adriaan P., van Vlijmen, Herman W. T., Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578754/
https://www.ncbi.nlm.nih.gov/pubmed/23436985
http://dx.doi.org/10.1371/journal.pcbi.1002899