Ectopic Expression of Ptf1a Induces Spinal Defects, Urogenital Defects, and Anorectal Malformations in Danforth's Short Tail Mice

Danforth's short tail (Sd) is a semidominant mutation on mouse chromosome 2, characterized by spinal defects, urogenital defects, and anorectal malformations. However, the gene responsible for the Sd phenotype was unknown. In this study, we identified the molecular basis of the Sd mutation. By...

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Detalles Bibliográficos
Autores principales: Semba, Kei, Araki, Kimi, Matsumoto, Ken-ichirou, Suda, Hiroko, Ando, Takashi, Sei, Akira, Mizuta, Hiroshi, Takagi, Katsumasa, Nakahara, Mai, Muta, Mayumi, Yamada, Gen, Nakagata, Naomi, Iida, Aritoshi, Ikegawa, Shiro, Nakamura, Yusuke, Araki, Masatake, Abe, Kuniya, Yamamura, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578775/
https://www.ncbi.nlm.nih.gov/pubmed/23436999
http://dx.doi.org/10.1371/journal.pgen.1003204

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