Alpha-Tomatine Attenuation of In Vivo Growth of Subcutaneous and Orthotopic Xenograft Tumors of Human Prostate Carcinoma PC-3 Cells Is Accompanied by Inactivation of Nuclear Factor-Kappa B Signaling

BACKGROUND: Nuclear factor-kappa B (NF-κB) plays a role in prostate cancer and agents that suppress its activation may inhibit development or progression of this malignancy. Alpha (α)-tomatine is the major saponin present in tomato (Lycopersicon esculentum) and we have previously reported that it su...

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Detalles Bibliográficos
Autores principales: Lee, Sui-Ting, Wong, Pooi-Fong, He, Hui, Hooper, John David, Mustafa, Mohd Rais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578807/
https://www.ncbi.nlm.nih.gov/pubmed/23437404
http://dx.doi.org/10.1371/journal.pone.0057708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578807/
https://www.ncbi.nlm.nih.gov/pubmed/23437404
http://dx.doi.org/10.1371/journal.pone.0057708

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