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A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

BACKGROUND: Cancer stem cells (CSC) are thought to be responsible for tumor maintenance and heterogeneity. Bona fide CSC purified from tumor biopsies are limited in supply and this hampers study of CSC biology. Furthermore, purified stem-like CSC subpopulations from existing tumor lines are unstable...

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Detalles Bibliográficos
Autores principales:	Mertins, Susan D., Scudiero, Dominic A., Hollingshead, Melinda G., Divelbiss, Raymond D., Alley, Michael C., Monks, Anne, Covell, David G., Hite, Karen M., Salomon, David S., Niederhuber, John E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578829/ https://www.ncbi.nlm.nih.gov/pubmed/23437320 http://dx.doi.org/10.1371/journal.pone.0057099

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