Intravenous Glial Growth Factor 2 (GGF2) Isoform of Neuregulin-1β Improves Left Ventricular Function, Gene and Protein Expression in Rats after Myocardial Infarction

AIMS: Recombinant Neuregulin (NRG)-1β has multiple beneficial effects on cardiac myocytes in culture, and has potential as a clinical therapy for heart failure (HF). A number of factors may influence the effect of NRG-1β on cardiac function via ErbB receptor coupling and expression. We examined the...

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Detalles Bibliográficos
Autores principales: Hill, Michael F., Patel, Amish V., Murphy, Abigail, Smith, Holly M., Galindo, Cristi L., Pentassuglia, Laura, Peng, Xuyang, Lenneman, Carrie G., Odiete, Oghenerukevwe, Friedman, David B., Kronenberg, Marvin W., Zheng, Siyuen, Zhao, Zhongming, Song, Yanna, Harrell, Frank E., Srinivas, Maya, Ganguly, Anindita, Iaci, Jennifer, Parry, Tom J., Caggiano, Anthony O., Sawyer, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578842/
https://www.ncbi.nlm.nih.gov/pubmed/23437060
http://dx.doi.org/10.1371/journal.pone.0055741

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