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Inhibition of Nuclear Factor-κB Activation in Pancreatic β-Cells Has a Protective Effect on Allogeneic Pancreatic Islet Graft Survival

Pancreatic islet transplantation, a treatment for type 1 diabetes, has met significant challenges, as a substantial fraction of the islet mass fails to engraft, partly due to death by apoptosis in the peri- and post-transplantation periods. Previous evidence has suggested that NF-κB activation is in...

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Detalles Bibliográficos
Autores principales: Eldor, Roy, Abel, Roy, Sever, Dror, Sadoun, Gad, Peled, Amnon, Sionov, Ronit, Melloul, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578930/
https://www.ncbi.nlm.nih.gov/pubmed/23437272
http://dx.doi.org/10.1371/journal.pone.0056924