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Technical Advance: Measurement of iNKT cell responses at the single-cell level against rare HIV-1-infected dendritic cells in a mixed culture

iNKT cells recognize lipid antigens, such as α-GalCer, presented in complex with CD1d expressed by DCs. Exposure of DCs to HIV-1 can lead to productive infection, and it was demonstrated recently that HIV-1 inhibits CD1d surface expression in an apparent mode of immune evasion. However, studies of t...

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Detalles Bibliográficos
Autores principales: Andersson, Sofia K., Paquin-Proulx, Dominic, Kroll, Mirko, Sandberg, Johan K., Moll, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579026/
https://www.ncbi.nlm.nih.gov/pubmed/23264676
http://dx.doi.org/10.1189/jlb.1012489