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Taxifolin Glycoside Blocks Human ether-a-go-go Related Gene K(+) Channels

Taxifolin glycoside is a new drug candidate for the treatment of atopic dermatitis (AD). Many drugs cause side effects such as long QT syndrome by blocking the human ether-a-go-go related gene (hERG) K(+) channels. To determine whether taxifolin glycoside would block hERG K(+) channels, we recorded...

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Detalles Bibliográficos
Autores principales: Yun, Jihyun, Bae, Hyemi, Choi, Sun Eun, Kim, Jung-Ha, Choi, Young Wook, Lim, Inja, Lee, Chung Soo, Lee, Min Won, Ko, Jae-Hong, Seo, Seong Jun, Bang, Hyoweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579103/
https://www.ncbi.nlm.nih.gov/pubmed/23440017
http://dx.doi.org/10.4196/kjpp.2013.17.1.37